Blood
Submission Instructions and Questionnaire
Bearded Collie, Great Dane, Leonberger, Portuguese Water Dog,
Standard Poodle & West Highland White Terrier
CGAP Home FAQs Update Health of Previously Submitted Dogs
Addison's Disease (Hypoadrenocorticism)
A deficient secretion of both glucocorticoids and mineralcorticoids from the adrenal cortex. The cause is unknown, but in most cases, there appears to be an immune mediated destruction of the adrenal gland. Symptoms include inappetance, vomiting, lethargy and weakness. An ACTH stimulation test can be used for diagnosis. The test is an evaluation of the ability of the adrenal gland to secrete cortisol. Affected dogs show low cortisol concentrations, and no increase in cortisol following the ACTH test. Treatment includes fluid therapy, replacement of glucocorticoids and mineralcorticoids, and hormone therapy.
Blood
Submission Instructions and Questionnaire
Please note UC DAVIS CAMPUS
HOLIDAYS AND CLOSURES 2009-2010 if sending a blood sample
Please avoid the following dates for blood sample submission:
2009
November 11
November 26-27
December 21-31
2010
January 1
January 18
February 15
March 24-26
May 31
June 14-15
The campus is also closed on weekends
2009
Call for Blood Samples for Addison’s and Epilepsy Diseases
Although we continue to collect DNA from buccal swab samples, newer research technologies require DNA extracted from blood samples. Thus, we are seeking blood samples from affected and unaffected dogs. Affected dogs with veterinary diagnosis can be submitted from dogs of any age. For unaffected dogs, we need samples from dogs over the age of 7 years that are free from the disease.
This is an AKC Canine Health Foundation funded research study, also supported by the Bearded Collie Club of America, the Bearded Collie Foundation for Health, the Poodle Club of America, the Leonberger Club of America, the Portuguese Water Dog Foundation and the Great Dane Club of America, designed to characterize the mode of inheritance of Addison’s disease (primary hypoadrenocorticism). To characterize the mode of inheritance, with the ultimate goal of identifying a genetic marker linked to the disease, we need information on dogs that are affected and unaffected with the disease. If you are willing to participate in this study, please download a blood sample submission form or request a kit that contains a questionnaire on your dog’s health status and swabs for the collection of DNA. The FAQs link will answer many of your questions regarding the study. We appreciate your support and interest in the study.
All disease information referenced from the
UC Davis Book of Dogs
UC Davis book of dogs : the complete medical reference guide for dogs and puppies,
by the Faculty and Staff, School of Veterinary Medicine, University of California at Davis ;
edited by Mordecai Siegal, consulting editor, Jeffrey E. Barlough. 1st ed. New York : HarperCollins Publishers, 1995.