CGAP FAQs


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1.                  What breeds are under study?

2.                  What are the potential benefits of this study?

3.                  How much does it cost to participate in the study?

4.                  How do I submit DNA from my dog?

5.                  How do I submit a health update for my dog?

6.                  Why do you need a blood sample from my dog?

7.                  Are there risks associated with collecting blood from my dog?

8.                  Is there an age requirement for sampling my dog?

9.                  Do the submitted dogs need to be related?

10.              May I submit a sample from my mixed breed or purebred rescue dog?

11.              My dog has one of the diseases you are studying, but is not a breed listed, may I still request a kit?

12.              My dog does not have any of these diseases, should I still request a kit/send samples?

13.              Do I need to include a copy of my dog's pedigree with the samples?

14.              What if I donít have a pedigree at the time Iím sending my samples in?

15.              Will you send me individual results for my dog?

16.              What is included in the buccal swab kit?

17.              Do the swabs cause any discomfort to my dog?

18.              I dropped one of the swabs on the ground, should I still use it or should I request another one?

19.              The swab broke or my dog chewed it during sampling, should I still send it?

20.              The swab package says, ďDo not use on pregnant patientsĒ.

21.              What should I do with the swabs when Iím done sampling?

22.             Should I submit samples even if my dog is spayed or neutered?

23.        Iím going to a dog show, may I distribute buccal swab kits? 

24.              Is this an international study?

25.        Itís been longer than 10 - 14 days and I havenít received my kit yet.

26.        Who do I contact if I have a question?

27.        Are there other ways to request a kit besides the website?

28.        How long will this research take?  

29.             Who is funding these projects?

30.        How can I donate money to the project? 

 


1.  What breeds are under study?

 

For Addisonís disease: Bearded Collie, Great Dane, Leonberger, Portuguese Water Dog, Standard Poodle & West Highland White Terrier 

 

For Epilepsy disease: Belgian Tervuren, Belgian Sheepdog, Giant Schnauzer, English Mastiff, Miniature Poodle, Standard Poodle & Toy Poodle

 

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2.  What are the potential benefits of this study?

 

There is no guarantee that your dog will benefit from its participation in this study. However, such participation may provide veterinarians and researchers with additional information and a better understanding of canine diseases, which could ultimately influence the course of treatment or genetic testing to help your dog and other animals in the future.

 

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3.  How much does it cost to participate in the study?

 

There is no fee for participating in this study. However, to submit blood samples, there may be a fee charged by your veterinarian for the collection and shipping of the blood sample (some vets may waive the fee if the sample is for research purposes).  If your dogís sample is directly used in the development of a genetic test associated with this disorder, upon your written request after the test becomes commercially available, the results of the test for this dog will be provided to you at no cost.

 

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4.  How do I submit DNA from my dog?
 
There are two ways: a blood sample or a buccal swab sample. 
 
For the blood sample, the veterinarian of your choice will collect the blood from your dog which you submit along with the downloadable form (Download Blood Submission Instructions and Questionnaire)Please note, CGAP is not responsible for costs incurred for blood collection and shipping.  We require 3-5cc(ml) of whole blood in purple-topped (EDTA) blood tubes.  Some veterinarians may collect and ship samples at no charge for research purposes Ė please check with your veterinarian. 
 
For a buccal swab sample, when you request a kit (Request a Buccal Swab Kit), we send you a swab kit that includes detailed instructions.  Briefly, you place the swab on the inside of the dogís cheek and swirl vigorously and then mail the swabs and questionnaire back to us.

 

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5.  How do I submit a health update for my dog?
 
Please click here to submit a health update. We ask that you update the health information of your dog annually even if it is just to let us know your dog is still healthy.
 

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6.  Why do you need a blood sample from my dog?

 

Although we continue to collect DNA from buccal swab samples, newer research technologies require DNA extracted from blood samples.  Thus, we are seeking blood samples from affected and unaffected dogs.  Affected dogs with veterinary diagnosis can be submitted from dogs of any age.  For unaffected dogs, we need samples from dogs over the age of 7 years that are free from the disease.

 

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7.  Are there risks associated with collecting blood from my dog?

 

The risk involved in drawing blood is minimal. However, your dog may experience mild redness or bruising at the collection site. Additionally, the veterinarian you have chosen to do this procedure may clip the hair to facilitate visualization of the vein. The veterinarian who will be performing this procedure is the veterinarian of your choice, and the University of California Davis is not responsible for any complications associated with drawing the blood.

 

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8.  Is there an age requirement for sampling my dog?

 

For these initial studies, we prefer affected dogs of any age and unaffected older dogs (over 7 years old). If the health status of the dog changes after you have sent in the DNA sample, we ask that you please submit a health update annually even if the dog is still healthy. Please click here to submit a health update.

 

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9.  Do submitted dogs need to be related? 

 

For the initial approach we are taking, blood samples from unrelated dogs affected and unaffected dogs are the best. We ask for the pedigrees so we can ensure the dogs are not related to one another at the grandparent/great grandparent level.  However, the next step of evaluating transmission of the trait through the generations, requires related dogs; for those transmission studies buccal swab samples are sufficient, but a blood sample would still be preferred.

 

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10. May I submit a sample from my mixed breed or purebred rescue dog?

 

We are only collecting samples from purebred registered dogs of the breeds listed below.
 
If your dog is a purebred rescue and you do not have any pedigree information on the dog, we appreciate your interest, but for this study, we need samples from dogs with known parentage.
 
For Addison's disease: Bearded Collie, Great Dane, Leonberger, Portuguese Water Dog, Standard Poodle and West Highland Terrier

 

For Epilepsy disease: Belgian Sheepdog, Belgian Tervuren, Giant Schnauzer, Mastiff, Miniature Poodle, Standard Poodle, and Toy Poodle

 

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11.  My dog has one of the diseases you are studying, but is not a breed listed, may I still request a kit?

 

Sorry, we are collecting samples ONLY from the breeds indicated at this time.  
 
These breeds include: 

 

For Addison's disease: Bearded Collie, Great Dane, Leonberger, Portuguese Water Dog, Standard Poodle and West Highland Terrier

 

For Epilepsy disease: Belgian Sheepdog, Belgian Tervuren, Giant Schnauzer, Mastiff, Miniature Poodle, Standard Poodle, and Toy Poodle
 

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12. My dog does not have any of these diseases or disorders, should I still request a kit/send samples?
 

Yes!  We need samples from both affected AND unaffected dogs.   We are asking for affected dogs with veterinary diagnosis of any age.  For unaffected dogs, we need samples from dogs over the age of 7 years old that are free from the disease.

 

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13.  Do I need to include a copy of my dog's pedigree with the samples?

 

Yes.  A pedigree is very helpful in the collection of information for the database. Send a copy of the pedigree to: CGAP, Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616-8521

 

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14.  What if I donít have a pedigree at the time Iím sending my samples in?

 

Please include as much information as you have on your dogís relatives.  The sire and dam names are required on the information sheet.  

 

You may send a copy of the pedigree at a later time Ė include your contact information on the pedigree.  Send to: CGAP, Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616-8521

 

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15.  Will you send me individual results for my dog?

 

Individual results will not be available.   A summary report on the research findings will be available at the conclusion of the study. 


If a diagnostic test is developed and you have submitted a DNA sample and your dog was directly used in the development of the test, we will send you the results of that dog at no charge upon your written request following announcement of the test.

 

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16.  What is included in the buccal swab kit?
 
The kit includes an information sheet for owner/dog information, sample collection instructions, 3 swabs (cytology brushes) and an SASE (stamped for U.S. residents only). 

 

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17.  Do the swabs cause any discomfort to my dog?
 
The bristles on the swab are soft and should not cause any discomfort to the dog.

 

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18.  I dropped one of the swabs on the ground, should I still use it or should I request another one?

 

No, do not use the swab.  The swabs are sterile and should be treated carefully.  

You do not need to request another swab, we can still collect DNA from the other two swabs.

 

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19.  The swab broke or my dog chewed it during sampling, should I still send it?

 

Yes, as long as the bristles are intact.

 

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20.  The swab package says, ďDo not use on pregnant patientsĒ.

 

The swabs that we use are multi-purpose and the pregnancy disclaimer is for human patients only.  You may still use the swabs on your pregnant bitch. 

 

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21.  What should I do with the swabs when Iím done sampling?

 

Once you have sampled your dog, place each brush back into itís own wrapper, write the dogís name on each wrapper, and seal it with a paperclip or staple Ė do not tape it or place it in a Ziplocģ bag. If you are sampling more than one dog, sample one dog at a time so samples do not get mixed up.  Send the samples and all of the necessary information back in the enclosed SASE.  

 

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22.  Should I submit samples even if my dog is spayed or neutered?

 

Yes.

 

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23.  Iím going to a dog show, may I distribute buccal swab kits?

 

Yes.  You may request and distribute kits (but please check with the show rules and guidelines to make sure DNA kits can be distributed).  

 

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24.  Is this an international study?

 

Yes.  We send kits all over the world, however, we cannot provide return postage outside of the U.S.

 

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25.  Itís been longer than 10 - 14 days and I havenít received my kit yet.

 

If there are many requests, it may take longer than 10 - 14 business days for you to receive your kit(s).  Sometimes we are backordered, but we will post this on the website if that is the case.

 

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26.  Who do I contact if I have a question?

 

amoberbauer@ucdavis.edu

 

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27.  Are there other ways to request a kit besides the website?

 

Yes.  You may e-mail a request to amoberbauer@ucdavis.edu or mail a request to  

CGAP, Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616-8521

 

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28.  How long will this research take?

 

The study is ongoing and will take time until the mutations are identified.  Check back for news of progress.  

 

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29.  Who is funding these projects?

 

Projects are funded by the AKC Canine Health Foundation, Poodle Club of America, Seizures Disorder Committee of the Mastiff Club of America and various breed clubs and foundations.

 

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30.  How can I donate money to the project?

 

We appreciate your generosity.  You can make donations through the Animal Science Department.  Please click here for instructions on how to donate.  Thank You!

 

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